Immunomodulating drugs

Monoclonal Anti-Caspase 9 (mouse IgG1 isotype) is derived from the CAS9 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with a synthetic peptide corresponding to amino acids of human caspase 9

General description This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

Caspase-10 is a member of the peptidase C14A family and is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and

General description Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex. Immunogen a peptide corresponding to amino acids 2-17 of murine caspase-12.

Immunogen a synthetic peptide corresponding to amino acids within the large cleavage product of murine caspase-12. Application Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given

General description Caspase-12 (CASP12) is an immunomodulatory factor, that is present in the cytoplasmic side of the ER (endoplasmic reticulum). It is upregulated highly in muscle, liver and kidney.

Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Caspase-14 exists as 2 subunits (p19 and p10) and is highly expressed in embryonic but not adult tissues.

ANTI-CASPASE-2 ANTIBODY CLONE 2Z10F1 RABBIT MONOCLONAL

Anti-Caspase 3 Antibody is suitable for use in IHC (frozen), IHC (paraffin), and WB. Expect a band approximately 31.

Anti-Caspase-3 Antibody has been tested for use in ELISA, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 31 kDa in Western Blots of specific cell lysates and tissues.

Specificity This antibody reacts to human full length caspase-3 (35 kDa) and the large fragment of caspase-3 resulting from cleavage (17 kDa). Immunogen Synthetic peptide corresponding to residues within human Caspase-3 subunit p17 Features and

Anti-Caspase-3 Antibody, Cleaved (Ab-2) Rabbit, 50UG