Nonsteroidal anti inflammatory drugs NSAIDs

An enantiomer of ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form also inhibits activation of NF-&kappaB more effectively than (R)-ibuprofen (IC₅₀s = 62 and 122

A potent inhibitor of COX-1 and COX-2 (IC₅₀s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent.

A potent inhibitor of COX-1 and COX-2 (IC₅₀s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent.

A potent inhibitor of COX-1 and COX-2 (IC₅₀s = 1.9 and 27 nM, respectively), whereas the (R)-enantiomer is 100 to 1,000 times less potent.

(S)-Naproxen is a non-selective COX inhibitor. The IC₅₀ values for human recombinant COX-1 and -2 are 0.6-4.8 &microM and 2.0-28.4 &microM, respectively.

(S)-Piperidin-2-ylmethanol.

(S)-Piperidin-2-ylmethanol.

(S)-Piperidin-2-ylmethanol.

(S)-Piperidin-2-ylmethanol.

(S)-Piperidin-3-amine.

(S)-Piperidin-3-amine.

(S)-Piperidin-3-ol.