Nonsteroidal anti inflammatorys, synthesized

InformationAMG-47a AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of

InformationAMG-47a AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of

InformationAMG319 is a potent and selectivePI3Kδinhibitor withIC50of 18 nM, &gt:47-fold selectivity over other PI3Ks. Phase 2.TargetsPI3Kδ : PI3Kγ 18 nM: 850 nMIn vitroAMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM

Anti-ADCYAP1R1 ADCYAP receptor type I, 25ul UN 1687 6.1 PG2

Specificity Cyclooxygenase-2. Two isoforms of Prostaglandin H synthase are well characterized, namely COX1 and COX2.

Anti-EPN3 epsin 3, 100ul UN 1687 6.1 PG2

Anti-EPN3 epsin 3, 100ul UN 1687 6.1 PG2

Anti-EPN3 epsin 3, 25ul UN 1687 6.1 PG2

Anti-IRX3 iroquois homeobox 3, 100ul UN 1687 6.1 PG2

Anti-IRX3 iroquois homeobox 3, 25ul UN 1687 6.1 PG2

Anti-RSAD1 radical S-adenosyl methionine domain containing 1

Anti-RSAD1 radical S-adenosyl methionine domain containing 1