General description
Mitomycin C is an antitumor antibiotic.
Application
Mitomycin C has been used:
- to cease mitosis
- in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs)
- as mutagen in mutagenicity assay
Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.
Biochem/physiol Actions
Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.
Other Notes
For life science research only. Not for use in diagnostic procedures.
- UPC:
- 51111704
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10107409001