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MITOMYCIN C

Sigma Aldrich

Catalog No.
C15-1244-225
Manufacturer No.
10107409001
Manufacturer Name
Sigma-Aldrich
Quantity
2
Unit of Measure
MG
Price: $198.97
List Price: $306.10

Mitomycin C is an antitumor antibiotic. Application Mitomycin C has been used: to cease mitosis in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs) as mutagen in mutagenicity assay Mitomycin C is

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General description

Mitomycin C is an antitumor antibiotic.

Application

Mitomycin C has been used:

  • to cease mitosis
  • in phosphate buffer saline (PBS) for inactivation and plating mouse embryonic fibroblasts (MEFs)
  • as mutagen in mutagenicity assay

Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.

Biochem/physiol Actions

Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions. MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.

Other Notes

For life science research only. Not for use in diagnostic procedures.

UPC:
51111704
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
10107409001

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