MK-571 has been reported to be a selective competitive inhibitor of [3H]leukrotriene D4 (LTD4) binding to CysLT1 receptors. LTD4 has been shown to induce contractions in guinea pig trachea and human lung membranes. Cysteinyl leukotrienes have also been identified as important pro-inflammatory mediators, therefore making MK-571 an anti-inflammatory agent. This compound demonstrates inhibitory characteristics of Mdr-1 (multidrug resistance protein-1) mediated transport. Additionally, studies suggest that this agent can augment the effects of cytotoxic agents on cells|in vitro|. MK-571 is an inhibitor of MRP1 and CysLT1 Receptor. Specification: ≥96% Molecular Formula: C26H26ClN2O3S2·Na Molecular Weight: 537.07 PubChem CID: 16760569 Isomeric SMILES: CN(C)C(=O)CCSC(C1=CC=CC(=C1)/C=C/C2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)[O-].[Na+] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M331361-SCI_81f57f93e416b360d9c8d5d8abde129d.pdf
- UPC:
- 12352211
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M331361-5mg
- CAS:
- 115103-85-0
- Product Size:
- 5mg
- Hazard Statement Codes:
- H319:H335
- Precautionary Statement Codes:
- P261:P264:P271:P280
