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MLS000544460 (C007B-374757)

Catalog No.
C007B-374757
Mfr. No.
M649314-25mg
Mfr. Name
Aladdin Scientific
Qty/UOM
1
UOM
EA
Price: $1,034.88
List Price: $1,149.86

MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor with a K d of 2.0 μM and an IC 50 of 4 μM. MLS000544460 inhibit Eya2 phosphatase mediated cell migration and has anti-cancer activityIn VitroMLS000544460 does not bind Eya3

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MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor with a K d of 2.0 μM and an IC 50 of 4 μM. MLS000544460 inhibit Eya2 phosphatase mediated cell migration and has anti-cancer activityIn VitroMLS000544460 does not bind Eya3 phosphatase (ED). MLS000544460 (10 μM) inhibits Eya2-mediated cell migration in human Eya2, Eya2 phosphatase-dead (D274N), and YFP (as a negative control) expressing MCF10A cells. When Eya2 ED is dialyzed into 10 μM EDTA to remove Mg 2+ , it binds MLS000544460 with a higher affinity (K d =0.80 μM), indicating that this class of compounds does not require Mg 2+ for its interaction with the Eya2 ED. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Kd: 2.0 μM (Eya2 phosphatase), IC50: 4 μM (Eya2 phosphatase). Specification: 0.99 Molecular Formula: C17H12FN3O2S Molecular Weight: 341.36 PubChem CID: 7285259 Isomeric SMILES: C1=CC=NC(=C1)SC2=CC=C(O2)/C=N/NC(=O)C3=CC(=CC=C3)F
UPC:
51162000
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
M649314-25mg
CAS:
352336-36-8
Product Size:
25mg

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