DescriptionThe matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development.Preparation instructionsSuitable for measuring MMP-3 activity in various biological samples.PrincipleMatrix metalloproteinase-3 (MMP-3) assay kit, MMP-3 hydrolyzes a specific FRET (fluorescence resonance energy transfer) substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically (lex = 325 nm/lem = 393 nm). Th. Specifications and Purity: sufficient for 100fluorometrictests. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M486394-SCI_ec7ad46bf1c1702c1a6261720c81571a.pdf.
- UPC:
- 12171501
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 3.53 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M486394-1kit
- Product Size:
- 1kit
