Molecular Biology

Boc-His(Dnp)-OH

Boc-Tyr(tBu)-OH

Application Protein degrader building block BocA1V2PF1-NHC 10 -NH 2 enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers) technology.

Application Protein degrader building block BocA1V2PF1-NHC 6 -NH 2 enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers) technology.

Application Protein degrader building block BocA1V2PF1-NHPEG 1 -NH 2 hydrochloride enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein

Application Protein degrader building block BocA1V2PF1-NHPEG 3 -NH 2 enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers)

Application Protein degrader building block BocA1V2PF2-NHPEG 1 -NH 2 enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers)

Application Protein degrader building block BocA1V2PF2-NHPEG3-NH2 enables the synthesis of molecules for targeted protein degradation and SNIPER (specific and non-genetic inhibitor of apoptosis protein (IAP)-dependent protein erasers) technology.

Biochem/physiol Actions Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by

Biochem/physiol Actions Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by

Bone Morphogenetic Protein 2 is a member of the TGF-&#946 superfamily of cytokines that affect bone and cartilage formation. It is important for skeletal development during embryogenesis.

Biochem/physiol Actions Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.