Molecular Biology

Native creatine phosphokinase from rabbit muscle. Catalyzes the conversion of creatine and ATP to creatine phosphate and ADP.

A cell-permeable naphthol derivative that acts as a highly potent and selective inhibitor of cAMP response element-binding protein (CREB)-mediated gene transcription (IC50 = 81 nM by CREB RLuc reporter assay with transfected HEK 293T cells). Also

OCT4 is the key transcription factor (TF) that maintains pluripotency of embryonic stem cells and plays a critical role in reinstating cellular pluripotency. The expression of OCT4 is stringently silenced in differentiated cells.

CRISPR Cas9-D10A Nickase mRNA generated through in-vitro transcription which has been capped and polyA-tailed. This mRNA should be used in conjunction with two purified guideRNAs.

The CRISPR Cas9-D10A Nickase expression plasmids use the CMV promoter for strong transient expression of Cas9. Alternate promoters can be substituted by replacement of CMV using MluI and NheI.

This gene activation system is based on a fusion of inactive Cas9 (dCas9) to the catalytic histone acetyltransferase (HAT) core domain of the human E1A-associated protein p300. The dCas9-p300 activator expression plasmids use the CMV promoter for

All-in-one, ready-to-use Cas9 and guide RNA (gRNA) expression plasmids with GUS Reporter CRISPR Plant Cas9 products are intended for Agrobacterium-mediated plant transformation. The products are based on the type IIA CRISPR-Cas9 derived from

All-in-one, ready-to-use Cas9 and guide RNA (gRNA) expression plasmids with GUS Reporter CRISPR Plant Cas9 products are intended for Agrobacterium-mediated plant transformation. The products are based on the type IIA CRISPR-Cas9 derived from S

The CRISPR Integration Kit provides the essential genome editing reagents necessary to integrate a BstNI restriction site to the human KRAS locus. This kit is intended to serve as a tool to evaluate cell lines for ability to integrate new sequences

Recent publications using CRISPR/Cas9-mediated recombineering in E. coli tout editing efficiencies near 100% , making CRISPR/Cas9-mediated recombineering the most powerful bacterial genome engineering method to date.

Recent publications using CRISPR/Cas9-mediated recombineering in E. coli tout editing efficiencies near 100% , making CRISPR/Cas9-mediated recombineering the most powerful bacterial genome engineering method to date.

Universal negative control CRISPRs have been designed not to recognize any sequence in the human, mouse or rat genome. A single vector format is provided which includes the Cas9 expression cassette and gRNA sequence.