Molecular Biology

Application Use generally to inhibit serine, cysteine, aspartic, and metalloproteases Physical form 2mM AEBSF, 1mM EDTA, 130&#956M Bestatin, E-64 14&#956M , 1&#956M Leupeptin, 0.3&#956M Aprotinin when reconstituted in 100ml of buffer supplied

Protease inhibitor mix. Application Sample preparation often requires the inhibition of protease activity.

As powders, all reagents can be stored at 0 °C. Those reagents designated for room temperature and 2-8 °C storage do not require storage at 0 °C, but will not be adversely affected when stored at 0 °C.

Contains 50 mg of AEBSF, HCl ( Cat. No.

Manufactured for Sigma by Boston Biochem., Inc.

A cell-permeable, reversible inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (MCP 20S proteasome) in HT4 cells. Causes the accumulation of ubiquitinated proteins in neuronal cells.

A cell-permeable, reversible inhibitor of the chymotrypsin-like activity of the multicatalytic proteinase complex (MCP 20S proteasome) in HT4 cells. Causes the accumulation of ubiquitinated proteins in neuronal cells.

A potent, cell-permeable, and reversible proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC K i = 460 nM).

A potent, cell-permeable, and reversible proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC K i = 460 nM).

Proteasomes are large multi-subunit protease complexes, localized in the nucleus and cytosol, which selectively degrade intracellular proteins. They play a major role in the degradation of many proteins involved in cell cycling, proliferation, and

Contains 5 mg of ALLN (Cat. No.

Fluorogenic proteasome substrate (excitation maximum: 380 nm emission maximum: 460 nm). Fluorogenic proteasome substrate.