Microorganisms

Analysis Note To view the Certificate of Analysis for this product, please visit www.cytiva.

Analysis Note To view the Certificate of Analysis for this product, please visit www.cytiva.

A cell-permeable, reversible, and ATP-competitive inhibitor against multiple protein kinases, including, but not limited to, CaM kinase II (K i = 1.8 nM), myosin light chain kinase (K i = 20 nM), protein kinase A (K i = 18 nM), protein kinase C (K

A cell-permeable protein kinase inhibitor that inhibits CaM kinase II (K i = 1.8 nM), myosin light chain kinase (K i = 17 nM), protein kinase A (K i = 18 nM), protein kinase C (K i = 25 nM), and protein kinase G (K i = 20 nM).

A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/&#946-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation, resulting in diminished &#946-catenin/p300 interaction

Homozygous: Yes Cell Line Description This cell line is an Epstein-Barr Virus (EBV) transformed lymphoblastoid line and is part of the Human Leukocyte Antigen (HLA) Typed Collection maintained by the European Collection of Cell Cultures (ECACC).

​JND3229 JND3229 is a potent reversible inhibitor of EGFR C797S with an IC50 value of 5.8 nM. JND3229 also potently suppresses EGFR L858R/T790M and EGFR WT with IC50 values of 30.5 nM and 6.8 nM, respectively.

​JND3229 JND3229 is a potent reversible inhibitor of EGFR C797S with an IC50 value of 5.8 nM. JND3229 also potently suppresses EGFR L858R/T790M and EGFR WT with IC50 values of 30.5 nM and 6.8 nM, respectively.

Biochem/physiol Actions JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell antiproliferative activity. It is selective for

Application JNJ7777120 has been used as a histamine-4 receptor antagonist: to study its effects on the pro-inflammatory microglia in rats to study its effects on the Parkinson&#8242s-like pathology in rat brain to study its effects on the

Application JNJ7777120 has been used as a histamine-4 receptor antagonist: to study its effects on the pro-inflammatory microglia in rats to study its effects on the Parkinson&#8242s-like pathology in rat brain to study its effects on the

Application JWH-015 has been used to study its effect on tumor-evoked pain behavior. It has also been used to study its protective effects on rat brain mitochondria upon paraquat exposure.