Metalloprotease Inhibitors

Anti-FAM208A family with sequence similarity 208, member A,

Anti-FAM208A family with sequence similarity 208, member A,

Anti-MMP7 matrix metallopeptidase 7, 100ul UN 1687 6.1 PG2

Anti-MMP7 matrix metallopeptidase 7, 25ul UN 1687 6.1 PG2

Ras-related protein 1 GTPase activating protein 2 (RAP1GAP2) gene with 26 exons spanning 261 kilobases of genomic DNA, is mapped to human chromosome 17p13.3.

Analysis Note Assay (iodometric, calc.on anhydrous substance): &#8805 98.

A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC 50 = 4 &#181M and 8 &#181M for PTP1B 403 and PTP1B 298 , respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B

A cell-permeable cyclohexenecarboxylate that disrupts TLR4 interaction with adaptor molecules TIRAP and TRAM by selectively binding to TLR4, but not TLR1-3 or TLR5-10, via TLR4 intracellular Cys747 residue. Shown to effectively inhibit

A cell-permeable, biologically active peptide consisting of a carboxyl terminal sequence derived from the JNK-binding domain (JBD) and an amino terminal peptide containing the HIV-TAT 48-57 sequence. Blocks c-Jun NH 2 -terminal kinase (JNK)

The non-permeant JNK inhibitor peptide TI-JIP 153-163 (Cat. No.

A cell-permeable biphenylsulfonamido-hydroxamate compound that acts a potent and Zn 2+ -binding site-targeting inhibitor of MMP-2 (IC 50 = 12 nM). It exhibits good selectivity over MMP-9 and MMP-3 (IC 50 = 0.

A potent, selective, slow-binding and mechanism-based inhibitor of human gelatinases, MMP-2 (K i = 13.9 nM) and MMP-9 (K i = 600 nM).