Protease Inhibitors

A cell-permeable pyrazolopyrimidine compound that acts as a potent, reversible, and ATP-competitive inhibitor against both mTORC1 &amp mTORC2 (IC 50 = 30 &amp 58 nM, respectively, with 100 &#181M ATP). PP242 inhibits PKC&#945, p110&#947, and

A cell-permeable compound that selectively downregulates the expression of p21 (~10 &#181M), independent of p53.expression, at either transcription or post-transcriptional level.

A cell-permeable pyrazolo-napthalenyl urea compound that acts as a highly potent, slowly binding (IC 50 = 8 and 97 nM, respectively, against human p38&#945, respectively, with or without 2 h preincubation), but high affinity (t 1/2 of dissociation

The p75 NTR inhibitor Pep5 (Cat. No.

Highly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t &#189 = 145 h at

Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.

Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.

Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.

Aeruginosamides are linear ribosomal peptides found in cyanobacteria such as Microcystis aeruginosa. Like other cyanotoxins, aeruginosamides may inhibit serine proteases and protein phosphatases (PPs) or exhibit antithrombotic activity.

PrEST Antigen CREB3L2 cAMP responsive element binding protei

PrEST Antigen CREB3L4 cAMP responsive element binding protei

PrEST Antigen SERPINA10 serpin peptidase inhibitor, clade A