General description
Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.
Application
Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression.
Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.
Biochem/physiol Actions
MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.
Unit Definition
kynuramine deamination activity: One unit will deaminate 1 nanomole of kynuramine per minute at pH 7.4 at 37 deg C.
Shipping Information:
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- UPC:
- 51142560
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- M7441-1VL
- Temperature Control Device:
- Yes
