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MOUSE MONOCLONAL ANTI-HUMAN BETA-2- MICROGLOBULIN CLONE BM-63 ASCITES FLUID

Catalog No.
C005B-453545
Mfr. No.
M7398-.2ML
Mfr. Name
Sigma-Aldrich
Qty/UOM
0.2
UOM
ML
Price: $563.20
List Price: $625.78

General description β:-2-microglobulin is part of the human leukocyte antigen, where it represents the light chain. It is expressed on cell membranes and is made up of 99 amino acids.

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General description

β-2-microglobulin is part of the human leukocyte antigen, where it represents the light chain. It is expressed on cell membranes and is made up of 99 amino acids. β-2-microglobulin is part of the immunoglobulin superfamily. β−2-Microglobulin is a membrane glycoprotein of mammalian nucleated cells including lymphocytes.

Monoclonal anti-β-2-Microglobulin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

human β2-microglobulin and a lysate of a lymphoblastoid cell line.

Application

Monoclonal Anti-β2-Microglobulin antibody produced in mouse has been used in ELISA and immunofluorescent labelling.

Biochem/physiol Actions

β-2-microglobulin acts as a tumor marker and has been shown to be associated with dialysis-related amyloidosis. It may function as a structural part of the MHC Class I molecule.

Microglobulin may be elevated in the serum or urine of patients with systemic lupus erythematosus (SLE), rheumatoid arthritis, metal toxications, some viral infections and possibly malignant disorders and AIDS.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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UPC:
51201516
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
M7398-.2ML
Temperature Control Device:
Yes

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