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MONOCLONAL ANTI-CD15 ANTIBODY PRODUCED IN MOUSE (C005B-321707)

Catalog No.
C005B-321707
Mfr. No.
SAB4700284-100UG
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
EA
Price: $558.77
List Price: $620.86

General description Cluster of differentiation 15 (CD15), also known as fucosyltransferase 4 (FUT4)/ Lewis x blood group antigen, is encoded by the gene mapped to long arm of human chromosome 11q21. It is ubiquitously expressed in various tissues

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General description

Cluster of differentiation 15 (CD15), also known as fucosyltransferase 4 (FUT4)/ Lewis x blood group antigen, is encoded by the gene mapped to long arm of human chromosome 11q21. It is ubiquitously expressed in various tissues such as gastrointestinal tract, brain and leukocytes.

The antibody MEM-158 reacts with CD15, a cell membrane molecule 3-fucosyl-N-acetyllactosamine (3-FAL) strongly expressed on granulocytes, monocytes, macrophages, mast cells; it is also present on Langerhans cells and some myeloid precursors cells.

Immunogen

Human granulocytes

Application

The reagent is designed for Flow Cytometry analysis using 10 μL reagent / 100 μL of sample.

Biochem/physiol Actions

Cluster of differentiation 15 (CD15)/fucosyltransferase 4 catalyzes the synthesis of Lex on the surface of the proliferating cells, in organ buds progressing in mesenchyma, during human embryogenesis. Overexpression of the gene has been associated with development of various type of cancers such as colon cancer, pancreatic cancer, gastric cancer and lung adenocarcinoma. siRNAs of FUT1/4 can be used as a potent therapeutic agent in human LeY-expressing cancers.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Shipping Information:

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UPC:
51112015
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
SAB4700284-100UG
Temperature Control Device:
Yes

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