Monoclonal Anti-CD56-FITC antibody produced in mouse

General description

Prepared by conjugation of fluorescein isothiocyanate isomer 1 (FITC). This green dye is efficiently excited at 495 nm and emits at 525 nm.

Immunogen

A cloned human NK cell line termed JT3

Application

Monoclonal Anti-CD56-FITC antibody produced in mouse is suitable for fluorescence microscopy. It was also used for flow cytometric analysis.

Biochem/physiol Actions

Neural Cell Adhesion Molecule (NCAM or the cluster of differentiation CD56) is a homophilic binding glycoprotein. It is expressed on the surface of neurons, glia, skeletal muscle and natural killer cells. CD56 can also be expressed in normal immature granulocytes at different expression levels in regenerative bone marrow. It is associated with cardiac genes induced by metabolic stress and its expression is associated with worsening hemodynamic parameters and major metabolic genes. CD56 is involved in left ventricular remodeling and can be implicated in heart failure. It is is developmentally regulated and may have an important role in cardiac development.

Physical form

Solution in phosphate buffered saline, pH 7.4, containing 0.2% gelatin and 0.08% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.