Immunogen

CNN1 (AAH22015, 1 a.a. ~ 297 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKTKGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA

Biochem/physiol Actions

Calponin 1 (CNN1) plays a key role in regulation of smooth muscle contraction in various physiological situations. Measurement of CNN1 level in maternal serum is considered to be a potent method for the short-term prediction of preterm birth in women with threatened preterm labor. CNN1 also acts as a cardiac and smooth muscle differentiation marker. In addition, it is also implicated in the actomyosin stabilization and cell motility repression.

Physical form

Solution in phosphate buffered saline, pH 7.4

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