Monofinity A Resin Prepacked Column 5mlx5,5ml prepacked x 5

Protein A affinity chromatography resin is the most commonly applied method for the isolation and purification of IgG. Protein A is a cell wall component found in several strains of Staphylococcus aureus . It has five high affinity binding sites capable of binding specifically to the Fc region of immunoglobulin molecules from several species. Covalently immobilized Protein A matrices have been extensively used to purify IgG from several species of mammals. GenScript's Monofinity A Resin is made of recombinant protein A as ligand, which not only keeps the specific binding capacity to Fc region of immunoglobulin molecules, but also enhances chemical stability under Cleaning-in-place (CIP) conditions. The typical dynamic binding capacity is more than 30 g human IgG/L settled resin. There is no significant decrease of binding capacity after purification/CIP for 200 cycles. In the meanwhile, the Monofinity A Resin has a low leakage of ligand (< 15 ng ligand/mg IgG) over a number of purification/CIP cycles. As a high quality antibody purification resin, it is highly suitable for large scale antibody purification, and meets the purification requirements of industry-scale customers.