Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with anti-EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.In VitroMosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC 50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: EV71,bacterial. Specification: 0.99 Molecular Formula: C17H14O5 Molecular Weight: 298.29 PubChem CID: 471722 Isomeric SMILES: COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
- UPC:
- 51341805
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M647485-10mg
- CAS:
- 740-33-0
- Product Size:
- 10mg
