MPP DIHYDROCHLORIDE HYDRATE (C005B-453607)

Catalog No.: C005B-453607
Mfr. No.: M7068-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $423.55

List Price: $470.61

General description Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol. Application MPP dihydrochloride hydrate has been used as an estrogen receptor α: antagonist: in human breast

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Description
Specifications

General description

Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol.

Application

MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:

in human breast cancer MCF-7 cells
to pre-treat endometrial ex vivo organ cultures (EVOCs)
to treat pituitary glands to monitor luteinizing hormone secretion

Biochem/physiol Actions

MPP dihydrochloride is a specific estrogen receptor α antagonist.

Methyl-piperidino-pyrazole hydrate (MPP) is an agonist for estrogen receptor α and lacks any ligand functionality with estrogen receptor (ER)β. It promotes silibinin induced apoptosis in human breast cancer MCF-7 cells.

UPC:: 51183706
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: M7068-10MG
CAS:: 911295-24-4

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