MUC1 Mouse mAb (C09-0741-976)

Mouse anti Human MUC1 antibody; , Monoclonal (C1), could be used for WB and so on.Application:WB: 0.01-2 µg/mLProtein FunctionThe alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. Specifications and Purity: mAb (C1); Mouse anti Human MUC1 antibody; WB; Unconjugated.