General description
MUC5AC is a high molecular weight glycoprotein classified as a secreted mucin produced by epithelial cells. MUC5AC is preferentially expressed in non-neoplastic gastric tissue and benign respiratory tract tissue. During neoplastic transformation, mucin expression may be altered within these tissues leading to particular patterns of expression. Cytoplasmic expression of MUC5AC can be seen in adenocarcinomas of the gastrointestinal tract, particularly those of the esophagus and stomach, as well as the pancreatobiliary tract including cholangiocarcinomas. Other tumors expressing MUC5AC include carcinomas of theendometrium and lung. MUC5AC may also be seen in Paget’s disease.
Quality
IVD | IVD | IVD | RUO |
Linkage
MUC5AC Positive Control Slides, Product No. 292S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
biological source: mouse. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: MRQ-19, monoclonal. description: For In Vitro Diagnostic Use in Select Regions (See Chart). form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (292M-94), vial of 0.5 . mL concentrate (292M-95), bottle of 1.0 . mL predilute (292M-97), vial of 1.0 . mL concentrate (292M-96), bottle of 7.0 . mL predilute (292M-98). manufacturer/tradename: Cell Marque™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500. isotype: IgG1. control: stomach. shipped in: wet ice. storage temp.: 2-8°C. visualization: cytoplasmic. Gene Information: human ... MUC5AC(4586).- UPC:
- 12352203
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 292M-94