General description
N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride, also known as EDAC HCl or WSC, is a water-soluble condensing reagent. EDAC HCl is generally used to couple carboxylic acids with amines to form amides. The by-product urea is water-soluble and can be removed from immiscible reaction milieux by extraction with water. It is principally utilized in solution-phase peptide synthesis and as a zero-length crosslinker for protein modification.
Application
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC hydrochloride) can be used as:
- A water-soluble carbodiimide to facilitate peptide coupling reactions in alcohols.
- A coupling agent along with HOBt to synthesize poly(glutamic acid) (PGA) polypeptides for the creation of non-fouling polypeptides that could be useful in a variety of biomedical applications.
- A coupling reagent for the efficient synthesis of teriflunomide at the industrial scale.
- UPC:
- 51285310
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 8009070025