N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone (C09-0986-275)

N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone is also known as 3-oxo-C|16|:1-Δ|11|cis-(L)-HSL. The N-acylated homoserine lactones (AHLs) comprise one class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone. Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C|4|-C|18|), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. An unspecified positional and geometric isomer of 3-oxo-C|16|:1-(L)-HSL is produced by the F2/5 strain of A. vitis, the bacterium responsible for grape crown gall and its resulting loss of agricultural productivity. Specification: A solution in acetonitrile Molecular Formula: C20H33NO4 Molecular Weight: 351.5 PubChem CID: 53394019 Isomeric SMILES: CCCCCCC=CCCCCCC(=O)CC(=O)NC1CCOC1=O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N339723-SCI_89f83e80596ae7a71a9f2f974835c87b.pdf