Amino Acid Sequence
NAc-Ile-Glu-Thr-Asp-pNA
Application
Chromogenic substrate for caspase 8 and granzyme B.
Biochem/physiol Actions
IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.
Molecular Weight: 638.62. Empirical Formula: C27H38N6O12. Quality Level: 200. Assay: ≥. 95%. form: powder. storage temp.: −. 20°C. SMILES string: CC[C@H](C)[C@H](NC(C): O)C(: O)N[C@@H](CCC(O): O)C(: O)N[C@@H](C(C)O)C(: O)N[C@@H](CC(O): O)C(: O)Nc1ccc(cc1)[N+]([O-]): O. InChI: 1S/C27H38N6O12/c1-5-13(2)22(28-15(4)35)26(42)30-18(10-11-20(36)37)24(40)32-23(14(3)34)27(43)31-19(12-21(38)39)25(41)29-16-6-8-17(9-7-16)33(44)45/h6-9,13-14,18-19,22-23,34H,5,10-12H2,1-4H3,(H,28,35)(H,29,41)(H,30,42)(H,31,43)(H,32,40)(H,36,37)(H,38,39)/t13-,14+,18-,19-,22-,23-/m0/s1. InChI key: FHURKTIGZAIQGR-BQCLNCLCSA-N. Gene Information: human ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002)mouse ... CFLAR(117279), GZMB(171528)
rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
- UPC:
- 51284013
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A9968-5MG