Amino Acid Sequence
NAc-Leu-Glu-His-Asp-AFC
General description
Amino acid derivatives of 7-amido-4-trifluoromethylcoumarin (AFC) are blue in fluorescence microscopy.
Application
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin has been used to assay caspase 9 activity using a substrate-based fluorimetric detection assay
Molecular Weight: 765.69. Empirical Formula: C33H38O11N7F3. Quality Level: 200. Assay: ≥. 95% (HPLC). form: powder. color: white. solubility: DMSO/DMF: 20 . mM. storage temp.: −. 20°C. SMILES string: CC(C)C[C@H](NC(C): O)C(: O)N[C@@H](CCC(O): O)C(: O)N[C@@H](Cc1c[nH]cn1)C(: O)N[C@@H](CC(O): O)C(: O)Nc2ccc3c(OC(: O)C: C3C(F)(F)F)c2. InChI: 1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1. InChI key: HULKIXRFKRCRHD-ZJZGAYNASA-N. Gene Information: human ... CARD9(64170), CASP9(842)mouse ... CARD9(332579), CASP9(12371)
rat ... CARD9(64171), CASP9(58918). Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).
- UPC:
- 51422209
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A5845-5MG