Biochem/physiol Actions
n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.
Features and Benefits
This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Molecular Weight: 378.50. Empirical Formula: C22H34O5. Quality Level: 100. Assay: ≥. 98% (HPLC). form: powder. color: white. solubility: DMSO: >. 65 . mg/mL. storage temp.: 2-8°C. SMILES string: CCCCCCCCC(: O)c1c(O)cc(O)cc1CC(: O)OCCCCC. InChI: 1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3. InChI key: FCKDHZVFIMRCNM-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302. Precautionary Statements: P264 - P270 - P301 + P312 - P501. Hazard Classifications: Acute Tox. 4 Oral. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51142405
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A0987-25MG