General description
N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies.
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Application
N-Maleoyl-β-alanine (3-maleimidopropanoic acid, N-(2-carboxyethyl)maleimide)) is the suitable reagent used in the following studies:
- To decrease the biotin binding affinity of Avd(S16C) (avidin with a single point mutation S16C).
- As a side chain reactive agent to modify tryptic peptides that result in mass shifts indicating the presence of cysteine residues.
- To preblock Xenopus laevis oocytes for exposed cysteines used as an expression system in the study of conformational changes in cASIC1a Receptors.
- As a protective agent for keratin fiber in high temperature process.
- As a non-cleavable maleimido moiety during the synthesis of tetrawalled molecular umbrella-octaarginine conjugates.
- Synthesis of organotin carboxylates of N-Maleoyl-β-alanine.
- To functionalize the gold surfaces to interact with cysteine-modified peptide.
- Preparation of cross-linked dextran–poly(ethylene glycol) hydrogel substrate.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
- UPC:
- 51171528
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 394815-250MG