General description
N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts.
N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts.
Application
N, N-Diisopropylethylamine can be used as a base:
- In the palladium (0)-catalyzed alkoxy carbonylation of allyl phosphates and acetate.
- In the selective enolate formation along with boryl triflates.
- In the C–N coupling of aryl halides with nitroarenes in the presence of nickel catalyst.
N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides.
- UPC:
- 51144116
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 496219-2L