General description
N, N-Dimethylformamide (DMF) is an organic compound commonly used as a reagent as well as a solvent in organic synthesis. It plays multiple roles in various reactions such as formylating agent, dehydrating agent, reducing agent as well as a catalyst.
Application
DMF can be used as:
- A formylating agent for organometallic compounds.
- A reactant to prepare Vilsmeier reagent by reacting with phosphorus oxychloride.
- A reagent for amination of aryl chlorides in the presence of potassium t-butoxide.
- A reducing agent for metal salts to prepare metal colloids.
- A catalyst for the regioselective silylation of unprotected carbohydrates.
DMF can also be used in the following:
- DMF-Phosgene catalytic system is used to prepare alkyl halides from alcohols.
- DMF-POCl3 is used to convert acyclic and cyclic enolizable ketones to β-chloro-α, β-unsaturated aldehydes.
- DMF-POCl3 is used to synthesize quinoline-3-carbaldehydes from acylanilides.
- DMF-SOCl2 combination is used to dehydrate oximes to nitriles.
- DMF-Ag2O converts α-bromopropionamides to oxazolidinones.
- DMF is frequently used as a solvent in many chemical reactions, which require a high solvency power.
Solvent for many hydrophobic organic compounds.
- UPC:
- 51144116
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 319937-4X4L
