Application
N,N-Dimethylhydrazine can react with:
- β-Naphthol via radical amination to form 1-amino-2-naphthol.
- 2-Chloro- and 2,2-dichloro-(bromo)vinyl ketones via regioselective heterocyclization to form 3-substituted 1-methyl(5-halo)pyrazoles.
- Terminal alkynes in the presence of TpRuCl(PPh3)2 (Tp = tris(pyrazolyl)borate) to form nitriles.
N,N-Dimethylhydrazine along with ferric chloride hexahydrate forms an effective reduction system for:
- Synthesizing DNA binding pyrrolo[2,1-c][1,4]benzodiazepine (PBD) imines via reductive cyclization of the corresponding nitro aldehyde.
- Transforming a variety of nitroarenes and azido compounds into the corresponding anilines and amino compounds, respectively.
Biochem/physiol Actions
Lung and colon tumor initiator in experimental animal model.
- UPC:
- 51391714
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- D161608-100G