A selective, endogenous TRPV1 agonist that is a “hybrid” analog, which incorporates components of both the AEA-like and dopamine neurotransmitter pathways; binds to the human recombinant TRPV1 (Ki = 36 nM) with equipotency to that of capsaicin and slightly more potency than that of N-arachidonoyl dopamine; causes hyperalgesia and nocifensive behavior that is blocked by the TRPV1 antagonist iodo-resiniferatoxin; has weak affinity for the rat CB1 receptor (Ki = 1.6 µM) and is a very weak inhibitor of FAAH; inhibits 5-LO from rat RBL-1 cells (IC50 = 7.5 nM).
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- UPC:
- 51373442
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10115-50
- CAS:
- 105955-11-1
- Model Number:
- C834T50
- Temperature Control Device:
- Yes