General description
This building block is prepared from highly purified PEG to ensure homogeneous products free from contaminating PEG oligomers. In this derivative the azido group acts as an orthogonally masked amine; it is stable to both TFA and piperidine but is easily converted to an amine by treatment with phosphines or thiols. For a similar spacer, see reference [1]. This material is now only available as an oil.
Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS
Literature references
[1] J. Mack, et al. (1999) J. Peptide Sci., 6, 135.
Linkage
Replaces: 01-63-0103
Analysis Note
Color (visual): slight yellow to yellow
Appearance of substance (visual): oil
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 41116113
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 8510210001
