NANOFABTX(TM) - NATURAL FOLATE LIPID MIX; FOR SYNTHESIS OF FOLATE FUNCTIONALIZED LIPOSOMES FOR TARGETED DELIVERY (C005B-254207)

Application

NanoFabTx^™ Natural Folate Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of folate-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery applications without the need for lengthy trial-and-error optimization.
NanoFabTx^™ Natural Folate Lipid Mix is a lyophilized, curated, lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve liposomes of approximately 100nm in diameter. The synthesized folate-functionalized liposomes can be used to selectively target cells which overexpress folate receptors such as HeLa cells and delivery hydrophilic or hydrophobic drugs, including therapeutics that are thermo-sensitive.

Features and Benefits

• A ready-to-use nanoformulation lipid blend for the synthesis of folate-functionalized liposomes without the need for high temepratures
• Step-by-step protocols developed and tested by our formulation scientists
• Flexible synthesis tool to create uniform and reproducible liposomes
• Optimized to make liposomes around 100 nm with low polydispersity
• Optimized lipid blend for folate-functionalized liposomes for therapeutic encapsulation

For microfluidic liposome synthesis of azide-functionalized liposomes, the NanoFabTx^™- Natural Folate Lipid Mix can be used with the the NanoFabTx^™Microfluidic - nano device kit (Cat.No. 911593). The NanoFabTx^™Microfluidic - nano device kit includes the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

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