NEK6 inibitor 8 (ZINC05007751) is a novel inhibitor of the NIMA-associated kinase NEK6 with an IC50 of 3.4 uM, Compound 8 was highly selective for NEK1 and NEK6, whereas no significant activity was observed for NEK2, NEK7, and NEK9; dispersed antiproliferative activity against a panel of human cancer cell lines (IC50 < 100 uM).
Specifictaions: ≥98%
PubChem CID: 2275754
Isomeric SMILES: CC\1=C(C(=O)NC(=O)/C1=C\C2=CC=C(O2)C3=CC=CC=C3)C#N
- UPC:
- 51442437
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N769774-10mg
- CAS:
- 591239-68-8
- Product Size:
- 10mg