Application
Neostigmine bromide has been used as an acetyl cholinesterase (AChE) inhibitor:
- to control reaction specificity of acetylcholinesterase in coronal organ of Botryllus schlosseri.
- to study its effects on abnormal contraction of pyloric circular smooth muscle strips (PCSMS).
- to study its effects on depolarization of bag cell neurons.
Biochem/physiol Actions
Neostigmine bromide is a quaternary amine. It is involved in elongating and boosting the muscarinic and nicotinic effects of acetylcholine by inhibiting cholinesterase activity. It is used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers.
Reversible inhibitor of acetylcholinesterase that is similar to eserine, but does not cross the blood-brain barrier.
Features and Benefits
This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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- UPC:
- 51151500
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- N2001-10G
- CAS:
- 114-80-7
- Temperature Control Device:
- Yes
