General description
Potent hypothalamic peptide neurotransmitter. An endogenous anti-psychotic compound that lowers blood pressure, increases vascular permeability, and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.
Potent hypothalamic peptide neurotransmitter. Lowers blood pressure, increases vascular permeability and increases plasma levels of glucagon, glucose, growth hormone and prolactin in rats. A modulator of noradrenergic activity. Heterogeneously distributed in the mammalian central nervous system and has many neurotransmitter-like characteristics.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Modulator of noradrenergic activity
Product does not compete with ATP.
Reversible: no
Packaging
Yes
Warning
Toxicity: Standard Handling (A)
Sequence
Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH
Other Notes
Kinkead, B., et al. 1999. Biol. Psychiatr.46, 340.
Tyler, B.M., et al. 1998. Brain Res. 792, 246.
Tsuda, K., and Masuyuma, Y. 1993. Am. J. Hypertens. 6, 473.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51151609
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 05-23-1200-5MG
- CAS:
- 39379-15-2
