Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC 50 s of 8.05, 9.83 and 0.57 μM for hMAO-B , NRF2 and QR2 . Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mIC50& Target:IC 50 : 8.05 μM (hMAO-B), 9.83 μM (NRF2), 0.57 μM (QR2)In Vitro:Nrf2-ARE/hMAO-B/QR2 modulator 1 (compound 4e) (100 μM; 24 hours) reduces the viability of SH-SY5Y cells by around 30%. Nrf2-ARE/hMAO-B/QR2 modulator 1 (1 μM; 24 hours for pre-treatment, then coincubated for another 24 hours with 10 nM okadaic acid (OBiological Activity:Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC 50 s of 8.05, 9.83 and 0.57 μM for hMAO-B , NRF2 and QR2 . Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated m. Specification: 10mM in DMSO Molecular Formula: C14H12N2O3 Molecular Weight: 256.26
- UPC:
- 51151534
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N661590-1ml
- Product Size:
- 1ml
