Product descriptionNSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity.Product ApplicationNSC697923 has been used as an inhibitor in STING-dependent NF-κB (nuclear factor-κB) activation after DNA damage, mediated by TRAF6 (TNF receptor-associated factor 6). Specification: ≥98% Molecular Formula: C11H9NO5S Molecular Weight: 267.26 PubChem CID: 394449 Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O2)[N+](=O)[O-] Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/N275218-SCI_3ba792cb35b281fdd2169442465546ed.pdf
- UPC:
- 12352208
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- N275218-10mg
- CAS:
- 343351-67-7
- Product Size:
- 10mg
- Hazard Statement Codes:
- H302:H318
- Precautionary Statement Codes:
- P264:P270:P280
