Application
Ochratoxin A has been used as a mycotoxin:
- to test its effect on metabolism and hypoxia in human embryonic kidney (HEK293) cells
- to test its cytotoxic effects in bovine mammary epithelial cells
- as a standard for gamma radiation studies with food products and in cytotoxic studies using Hep G2 cells
Biochem/physiol Actions
Ochratoxin A (OTA), a renal toxin, is produced majorly by Aspergillus and Penicillium fungal species. It is immunotoxic, teratogenic myelotoxic, and mutagenic. It effectively interrupts the intestinal barrier functions. OTA displays a long elimination half-life and stimulates the major inflammatory cytokines release.
Ochratoxin A is a mycotoxin found in food that is nephrotoxic and carcinogenic in the kidney and induces differentiation in cloned renal cell lines. Increases endoplasmic reticulum ATP-dependent Ca2+ pump activity.
Shipping Information:
Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.
More Information: https://cenmed.com/shipping-returns
- UPC:
- 41115813
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- O1877-25MG
- CAS:
- 303-47-9
