Olodanrigan (EMA401) Olodanrigan (EMA401, PD-126055, (S) PD-126055) is a highly selective, orally active, peripherally restricted antagonist of angiotensin II type 2 receptor (AT2R) . Olodanrigan (EMA401) analgesic action appears to involve the inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons.TargetsAT2R
Specification: Moligand™, ≥98%
Molecular Formula: C32H29NO5
Molecular Weight: 507.58
PubChem CID: 9937291
Isomeric SMILES: COC1=C(C2=C(CN([C@@H](C2)C(=O)O)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4)C=C1)OCC5=CC=CC=C5
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/O412324-SCI_0a5f1e88ffccc9b65daa93c81ec5cade.pdf
- UPC:
- 51373462
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 0.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- O412324-5mg
- CAS:
- 1316755-16-4
- Product Size:
- 5mg
- Hazard Statement Codes:
- H302:H335:H319:H315
- Precautionary Statement Codes:
- P305+P351+P338:P261
