Ophiobolin C

Ophiobolin C is a phytotoxic metabolite from the Ophiobolin class produced by many species of the genus|Bipolaris|. Studies suggest that Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells. In addition, the culture medium is a key component for the production of a specific Ophiobolin from the same organism. It has been reported that|B. maydis|will produce Ophiobolin A , B , and L if cultured in liquid medium, while in contrast produce Ophiobolin C and K in solid substratum medium. The structure of Ophiobolin C is comprised of five isoprene units linked together to form the backbone of the molecule. Specification: >98% Molecular Formula: C25H38O3 Molecular Weight: 386.6 PubChem CID: 11234566 Isomeric SMILES: C[C@@H](CCC=C(C)C)[C@H]1CC[C@]2([C@H]1C/C=C(/[C@@H]3[C@H](C2)[C@](CC3=O)(C)O)/C=O)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/O329418-SCI_9792a1b1a1a2e3b358deaddbce49c18f.pdf