Skip to main content

ORANGE-NHS LIVE CELL PH DYE (1EA= 1MG) (C005B-314850)

Catalog No.
C005B-314850
Mfr. No.
SCT265
Mfr. Name
Sigma-Aldrich
Qty/UOM
1
UOM
EA
Price: $558.77
List Price: $620.86

General description The BioTracker ™: exosome membrane labeling probe series can be used for staining of the membranes of purified exosomes, which in turn permits imaging of labeled exosomes taken up by cells.SCT265 does not cause

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

Adding to cart… The item has been added

General description

The BioTracker exosome membrane labeling probe series can be used for staining of the membranes of purified exosomes, which in turn permits imaging of labeled exosomes taken up by cells.SCT265 does not cause aggregation and has little effect on the properties of exosomes, permitting accurate observation of exosome dynamics.BioTracker exosome membrane labeling probes overcome issues with existing labeling dyes, including:1) self-particle formation2) an increase in size of the exosomes after labelingThree different fluorescence colors---green (SCT265), red (SCT266), and far red (SCT267)--- enable application in multiplexing experiments, such as observation of exosome localization in organelles.Add 10 uL DMSO to tube of green, red, or far red exosome membrane dye to create stock solution. SPECTRAL PROPERTIES:Ex 488nm/Em 490-540nmReferences:Kawata R, Oda S, Koya Y, Kajiyama H, Yokoi T. 2020. Macrophage-derived extracellular vesicles regulate concanavalin A-induced hepatitis by suppressing macrophage cytokine production. Toxicology. 443:152544.

Features and Benefits

This live cell probe fluoresces in the green spectral range when it binds to the lipid bilayer in exosome membranes.

Target description

Exosomes are a form of extracellular vesicle (EV), which can contribute to intercellular communication. To elucidate such communication, labeling techniques based on fluorescent dyes have been developed. Fluorescent dyes that label the cellular membrane are commonly used for exosome labeling because the lipid bilayer in exosomes is a suitable labeling target.

Storage and Stability

Store BioTracker Green Exosome Membrane Labeling Kit at 2 - 8 °C, protected from light.After resuspending in DMSO, store stock solution at -20 °C, protected from light.

Other Notes

This live culture probe for the detection of exosomes labels the lipid bilayers of exosomal membranes, enabling observation of the uptake of exosomes by cells. Exosomes should be purified before labeling.

Legal Information

BioTracker is a trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

UPC:
12171500
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
SCT265

Cenmed Satisfaction Guarantee
Cenmed Satisfaction Guarantee

At Cenmed, your confidence and satisfaction are paramount. We guarantee the quality and reliability of our extensive range of clinical and laboratory supplies. If you're not completely satisfied with your purchase, we offer a straightforward return process and dedicated support to resolve your concerns promptly. Our commitment ensures that you can order with confidence, knowing that Cenmed is dedicated to superior service and customer satisfaction. Trust us to meet your needs with every order, backed by our promise of excellence. Learn more in Help & FAQs.

Testimonial
"Cenmed provides me access to the same products/services normally reserved for much larger labs than mine. I was presently surprised by their product offering."

LAB DIRECTOR

Testimonial
"We utilized Cenmed's capabilities for a variety of projects around the world. They are a valued partner and supplier."

PHARMACEUTICAL SUPPLY CHAIN LEADER

Testimonial
"The reps are very good at finding products for customers in this period of supply chain issues."

SCOTT BEHMAN

Testimonial
"Your customer service has been excellent and makes me excited about purchasing with Cenmed in the future!!"

PROCUREMENT + BILLING COORDINATOR AT PHARMA.