p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC 50 of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC 50 =27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targetsForm:SolidIC50& Target:p38α MAPK 9.6 (pIC 50 ). Specification: 0.98 Molecular Formula: C27H33N5O3 Molecular Weight: 475.58 PubChem CID: 25145735 Isomeric SMILES: CC1=C(C=C(C=C1)C(=O)NC2CC2)N3C=CN=C(C3=O)NC(C)(C)C4=CC=CC=C4OCCNC
- UPC:
- 51203900
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P647104-25mg
- CAS:
- 1095003-80-7
- Product Size:
- 25mg
