PACMA 31 is an irreversible, protein disulfide isomerase (PDI) inhibitor with an IC50 of 10 μM. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues. PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Specification: 0.98 Molecular Formula: C₂₁H₂₂N₂O₆S Molecular Weight: 430.47 PubChem CID: 66555902 Isomeric SMILES: CCOC(=O)CNC(=O)C(C1=CC=CS1)N(C2=C(C=C(C=C2)OC)OC)C(=O)C#C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/P287528-SCI_5f86a7979ad5f4a372b18b1330176a7d.pdf
- UPC:
- 12352204
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- P287528-1mg
- CAS:
- 1401089-31-3
- Health Hazards:
- Toxic
- Product Size:
- 1mg
- Hazard Statement Codes:
- H301
- Precautionary Statement Codes:
- P264:P270:P301:P321:P330:P405:P501
