General description
Product Source: N-terminal FLAG-tagged, recombinant, human PAK1 amino acids 150-end, expressed by baculovirus in Sf21 insect cells.
This protein is a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Biochem/physiol Actions
Protein Target: PAK1
Packaging
Also available in 10μg size as catalog # 14-927 and in 250 μg as catalog # 14-927M.
Quality
Routinely evaluated by phosphorylation of peptide RRRLSFAEPG.
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Shipping Information:
Dry Ice Surcharge & Ice Pack Shipments: $40
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- UPC:
- 41116012
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 14-927
- Temperature Control Device:
- Yes
