General description
A highly potent competitive antagonist selective for nAChRs (IC50 = 5.5 nM). A very potent non-depolarizing skeletal muscle relaxant but no sedative or analgesic effects.
Biochem/physiol Actions
Primary Target
nAChR
Warning
Toxicity: Toxic (F)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Lowenick et al., 2001. Eur. J. Pharmacol.413, 31.
Melnikov, L., et al., 1999. Gen Pharmacol.33, 313.
Maestrone, E., et al., 1994. Br. J. Pharmacol.111, 283.
Fryer, D., et al., 1987. Naunyn Schmiedebergs Arch. Pharmacol.335, 367.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51152067
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 5052260001