PBIT (C15-1724-429)

Sigma Aldrich

Catalog No.: C15-1724-429
Manufacturer No.: SML1058-5MG
Manufacturer Name: Sigma-Aldrich
Quantity: 5
Unit of Measure: MG

Price: $283.96

List Price: $315.51

Biochem/physiol Actions S , S ′:-1,4-phenylenebis(1,2-ethanediyl)bis-isothiourea (PBIT) is an iNOS (inducible nitric oxide synthase) inhibito. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels

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Biochem/physiol Actions

S,S′-1,4-phenylenebis(1,2-ethanediyl)bis-isothiourea (PBIT) is an iNOS (inducible nitric oxide synthase) inhibito. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.

PBIT is a potent inhibitor of JARID1B (KDM5B) histone lysine demethylase that inhibits removal of H3K4me3 in UACC-812 cells. PBIT inhibits proliferation of cells overexpressing JARID1B. PBIT is selective for JARID1 enzymes and does not inhibit demethylases UTX or JMJD3.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

UPC:: 51361927
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
WeightUOM:: LB
MPN:: SML1058-5MG
Product Size:: 5/MG
CAS:: 2514-30-9

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