PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1) , with no effect on PTH type 2 receptor.In VitroPCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor. PCO371 induces cAMP production with an EC 50 of 2.4 μM in COS-7 cells expressing hPTHR1, and 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC 50 , 17 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:PTHR1. Specification: 0.98 Molecular Formula: C29H32F3N5O6S Molecular Weight: 635.65 PubChem CID: 76283707 Isomeric SMILES: CC1=CC(=CC(=C1CCS(=O)(=O)N2CCC3(CC2)C(=O)NC(=N3)C4=CC=C(C=C4)OC(F)(F)F)C)N5C(=O)NC(=O)C5(C)C
- UPC:
- 51182412
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P650805-50mg
- CAS:
- 1613373-33-3
- Product Size:
- 50mg
